Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CTSD | P07339 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30964113 | 0.91 | POLB (0.64) | POLBLMNATSHRALDH1A1GLA | |
| SCHEMBL19478687 | 0.81 | GLA (0.68) | POLBLMNATSHRALDH1A1GLA | |
| SCHEMBL25148143 | 0.78 | SMN1; SMN2 (0.45) | POLBTSHRALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL7472743 | 0.78 | SMN1; SMN2 (0.81) | POLBLMNATSHRUSP2SMN1; SMN2 | |
| SCHEMBL16412166 | 0.77 | SMN1; SMN2 (0.59) | POLBLMNATSHRALDH1A1GLA | |
| SCHEMBL25148548 | 0.77 | SMN1; SMN2 (0.49) | POLBLMNATSHRALDH1A1GLA | |
| SCHEMBL8276140 | 0.77 | ATM (0.50) | POLBLMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL8001888 | 0.77 | GLA (0.81) | POLBLMNATSHRALDH1A1GLA | |
| SCHEMBL31129062 | 0.76 | KMT2A (0.49) | POLBLMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL6203138 | 0.75 | SIGMAR1 (0.43) | TSHRUSP2SMN1; SMN2CTSDCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023061405-A1 | HIGHLY-STABLE TARGETED LINKER-DRUG CONJUGATE | 成都科岭源医药技术有限公司 | 2023-04-20 | — | — | WO | disclosed |