Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 4/20 | 0.42 |
| ▸ | NAMPT | P43490 | 12/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8221403 | 1.00 | ADAM17 (0.42) | ADAM17NAMPTTRPV1MEN1KMT2A | |
| SCHEMBL8276662 | 1.00 | ADAM17 (0.42) | ADAM17NAMPTTRPV1MEN1KMT2A | |
| SCHEMBL8221020 | 0.84 | RBP4 (0.46) | ADAM17TRPV1 | |
| SCHEMBL8221943 | 0.83 | CHRM4 (0.43) | ADAM17NAMPT | |
| SCHEMBL8217041 | 0.80 | CHRM4 (0.47) | ADAM17NAMPTMEN1KMT2A | |
| SCHEMBL13544350 | 0.80 | ADAM17 (0.47) | ADAM17NAMPTMEN1KMT2A | |
| SCHEMBL8273743 | 0.80 | ADAM17 (0.46) | ADAM17NAMPTMEN1KMT2A | |
| SCHEMBL8276666 | 0.79 | ADAM17 (0.43) | ADAM17NAMPTMEN1KMT2A | |
| SCHEMBL8274405 | 0.79 | ADAM17 (0.43) | ADAM17NAMPTMEN1KMT2A | |
| SCHEMBL8275285 | 0.78 | NAMPT (0.42) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |