Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 18/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8276118 | 0.90 | ADAM17 (0.43) | NAMPT | |
| SCHEMBL8274407 | 0.90 | ADAM17 (0.43) | NAMPT | |
| SCHEMBL12216389 | 0.89 | NAMPT (0.41) | NAMPT | |
| SCHEMBL8214539 | 0.89 | ADAM17 (0.45) | NAMPT | |
| SCHEMBL8275981 | 0.85 | NAMPT (0.42) | NAMPT | |
| SCHEMBL8273733 | 0.85 | NAMPT (0.43) | NAMPTHDAC2HDAC1 | |
| SCHEMBL8273768 | 0.85 | HPGDS (0.38) | NAMPTHDAC2HDAC1 | |
| SCHEMBL8273591 | 0.84 | ADAM17 (0.43) | NAMPTHDAC2HDAC1 | |
| SCHEMBL8273310 | 0.84 | GAA (0.44) | NAMPT | |
| SCHEMBL8273592 | 0.83 | HTT (0.46) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |