Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8281100 | 1.00 | APLNR (0.40) | APLNRALDH1A1GAAALOX12HTT | |
| SCHEMBL4432102 | 0.83 | ALDH1A1 (0.36) | APLNRALDH1A1GAAALOX12HTT | |
| SCHEMBL8282772 | 0.82 | APLNR (0.42) | APLNRAPP | |
| SCHEMBL8220973 | 0.82 | APLNR (0.42) | APLNRAPP | |
| SCHEMBL13862140 | 0.79 | APLNR (0.34) | APLNR | |
| SCHEMBL8281102 | 0.79 | APLNR (0.34) | APLNR | |
| SCHEMBL26125646 | 0.77 | NPC1 (0.33) | APLNRALDH1A1 | |
| SCHEMBL26125642 | 0.77 | NPC1 (0.33) | APLNRALDH1A1 | |
| SCHEMBL10347901 | 0.75 | ALDH1A1 (0.37) | ALDH1A1GAAALOX12HTTHIF1A | |
| SCHEMBL8281168 | 0.75 | MAPKAPK2 (0.36) | APLNRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005103055-A1 | PYRAZOLO-[4,3-e]-1,2,4-TRIAZOLO-[1,5-c]-PYRIMIDINE ADENOSINE A2A RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 2005-11-03 | — | — | WO | disclosed |