Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8220973 | 1.00 | APLNR (0.42) | APLNRPARP1PFKFB3RXRAGRIN1 | |
| SCHEMBL8281100 | 0.82 | APLNR (0.40) | APLNRAPP | |
| SCHEMBL8280147 | 0.82 | APLNR (0.40) | APLNRAPP | |
| SCHEMBL29825036 | 0.80 | CHRNA1 (0.35) | APLNR | |
| SCHEMBL8220969 | 0.79 | APLNR (0.36) | APLNRPARP1PFKFB3RXRAGRIN1 | |
| SCHEMBL18192822 | 0.77 | APLNR (0.40) | APLNRPARP1 | |
| SCHEMBL31073192 | 0.77 | APLNR (0.42) | APLNR | |
| SCHEMBL31042359 | 0.77 | APLNR (0.42) | APLNR | |
| SCHEMBL408604 | 0.77 | APLNR (0.42) | APLNR | |
| SCHEMBL8257350 | 0.75 | PARP1 (0.39) | APLNRPARP1PFKFB3RXRAGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005103055-A1 | PYRAZOLO-[4,3-e]-1,2,4-TRIAZOLO-[1,5-c]-PYRIMIDINE ADENOSINE A2A RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 2005-11-03 | — | — | WO | disclosed |