Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTRA1 | Q92743 | 18/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8282371 | 0.88 | CTSV (0.39) | HTRA1 | |
| SCHEMBL8246705 | 0.81 | DPP4 (0.43) | — | |
| SCHEMBL10139694 | 0.80 | NR1I2 (0.33) | HTRA1 | |
| SCHEMBL13251685 | 0.80 | HTRA1 (0.34) | HTRA1 | |
| SCHEMBL10173914 | 0.78 | CTSK (0.43) | — | |
| SCHEMBL12604926 | 0.78 | CTSK (0.43) | — | |
| SCHEMBL10173922 | 0.78 | CTSK (0.40) | — | |
| SCHEMBL12604925 | 0.78 | CTSK (0.40) | — | |
| SCHEMBL10174297 | 0.77 | KEAP1 (0.34) | HTRA1 | |
| SCHEMBL10173750 | 0.77 | KEAP1 (0.32) | HTRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005087721-A2 | COMPOUNDS AS INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORPORATION (US) | 2005-09-22 | — | — | WO | disclosed |