Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8280857 | 1.00 | MCHR1 (0.46) | MCHR1HRH3ALDH1A1L3MBTL1MAPT | |
| SCHEMBL14344778 | 0.89 | ALDH1A1 (0.43) | MCHR1ALDH1A1L3MBTL1MAPTL3MBTL3 | |
| SCHEMBL26617906 | 0.86 | ALDH1A1 (0.39) | MCHR1ALDH1A1L3MBTL1L3MBTL3 | |
| SCHEMBL20606198 | 0.86 | MCHR1 (0.46) | MCHR1HRH3L3MBTL1MAPTL3MBTL3 | |
| SCHEMBL20896382 | 0.86 | MCHR1 (0.46) | MCHR1HRH3L3MBTL1MAPTL3MBTL3 | |
| SCHEMBL24127456 | 0.84 | MAPT (0.47) | MCHR1HRH3MAPTL3MBTL3 | |
| SCHEMBL772201 | 0.84 | L3MBTL3 (0.37) | MCHR1ALDH1A1L3MBTL1MAPTL3MBTL3 | |
| SCHEMBL8152193 | 0.84 | KMT2A (0.41) | ALDH1A1L3MBTL1MAPTMAPK1 | |
| SCHEMBL10196415 | 0.84 | KMT2A (0.41) | ALDH1A1L3MBTL1MAPTMAPK1 | |
| SCHEMBL8138752 | 0.83 | HRH3 (0.41) | MCHR1HRH3ALDH1A1L3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080389-A1 | INDAZOLE-CARBOXAMIDE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS | THERAVANCE, INC. (US) | 2005-09-01 | — | — | WO | disclosed |