Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8281149 | 0.79 | ALDH1A1 (0.52) | GFERALDH1A1MAPTHTTGAA | |
| SCHEMBL14018752 | 0.77 | ALDH1A1 (0.68) | GFERALDH1A1MAPTHTTGAA | |
| SCHEMBL8279547 | 0.76 | P2RX1 (0.53) | GFERALDH1A1MAPTHTTTDP1 | |
| SCHEMBL20202313 | 0.75 | ALDH1A1 (0.66) | GFERALDH1A1MAPTHTTGAA | |
| SCHEMBL24876579 | 0.71 | LMNA (0.73) | GFERALDH1A1MAPTHTTGAA | |
| SCHEMBL6676320 | 0.70 | ALDH1A1 (0.55) | GFERALDH1A1MAPTHTTGAA | |
| SCHEMBL14018748 | 0.70 | ALDH1A1 (1.00) | GFERALDH1A1MAPTHTTTDP1 | |
| SCHEMBL4880800 | 0.70 | MAPT (0.79) | GFERALDH1A1MAPTHTTTDP1 | |
| SCHEMBL11571406 | 0.69 | CA1 (0.66) | GFERALDH1A1MAPTHTTGAA | |
| SCHEMBL1646021 | 0.69 | CA1 (1.00) | GFERALDH1A1MAPTHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005090298-A1 | SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2005-09-29 | — | — | WO | disclosed |