Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | GFER | P55789 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8278268 | 0.78 | GAA (0.50) | PDK2MAPTGFERALDH1A1GAA | |
| SCHEMBL14018765 | 0.76 | MAPT (0.66) | MAPTGFERALDH1A1GAAKMT2A | |
| SCHEMBL532896 | 0.75 | ACLY (0.65) | MAPTGFERALDH1A1GAAKMT2A | |
| SCHEMBL18553735 | 0.73 | HTR6 (0.61) | PDK2ALDH1A1LMNA | |
| SCHEMBL10988362 | 0.71 | KDM4E (0.48) | PDK2MAPTGFERALDH1A1GAA | |
| SCHEMBL28824858 | 0.70 | MAPT (0.60) | MAPTGFERALDH1A1GAAKMT2A | |
| SCHEMBL8278302 | 0.69 | ESR1 (0.55) | GFERALDH1A1GAASMN1; SMN2HSP90AA1 | |
| SCHEMBL28751618 | 0.69 | ALDH1A1 (0.56) | MAPTGFERALDH1A1GAAKMT2A | |
| SCHEMBL24876736 | 0.69 | KMT2A (0.63) | MAPTGFERALDH1A1GAAKMT2A | |
| SCHEMBL31679838 | 0.69 | KMT2A (0.63) | MAPTGFERALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005090298-A1 | SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2005-09-29 | — | — | WO | disclosed |