Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | PER2 | O15055 | 4/20 | 0.39 |
| ▸ | CRY1 | Q16526 | 4/20 | 0.39 |
| ▸ | CRY2 | Q49AN0 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13622636 | 1.00 | CTSK (0.39) | CTSKCTSLCTSBPER2CRY1 | |
| SCHEMBL13622674 | 0.96 | CTSK (0.41) | CTSKCTSLCTSBPER2CRY1 | |
| SCHEMBL8282033 | 0.96 | CTSK (0.41) | CTSKCTSLCTSBPER2CRY1 | |
| SCHEMBL8283754 | 0.86 | CA1 (0.50) | CTSKCTSLCTSBPER2CRY1 | |
| SCHEMBL13622641 | 0.86 | CA1 (0.50) | CTSKCTSLCTSBPER2CRY1 | |
| SCHEMBL13684451 | 0.81 | PER2 (0.40) | PER2CRY1CRY2 | |
| SCHEMBL12601000 | 0.81 | CTSK (0.37) | CTSKCTSLCTSBPER2CRY1 | |
| SCHEMBL13622697 | 0.81 | CTSK (0.37) | CTSKCTSLCTSBPER2CRY1 | |
| SCHEMBL8282064 | 0.78 | CA1 (0.38) | CTSKCTSLCTSBPER2CRY1 | |
| SCHEMBL13622721 | 0.78 | CA1 (0.38) | CTSKCTSLCTSBPER2CRY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730142-B1 | NOVEL KETOAMIDES WITH CYCLIC P4'S AS INHIBITORS OF NS3 SERINE PROTEASE OF HEPATITIS C VIRUS | SCHERING CORP (US) | 2011-06-29 | — | — | EP | disclosed |
| WO-2005085242-A1 | NOVEL KETOAMIDES WITH CYCLIC P4'S AS INHIBITORS OF NS3 SERINE PROTEASE OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2005-09-15 | — | — | WO | disclosed |