Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8282196 | 0.81 | MEN1 (0.41) | PIK3CDMEN1KMT2ATSHRGAA | |
| SCHEMBL8282904 | 0.79 | PIK3CD (0.40) | PIK3CDMEN1KMT2ATSHRGAA | |
| SCHEMBL8282193 | 0.79 | HTR1A (0.40) | PIK3CDMEN1KMT2ATSHRGAA | |
| SCHEMBL12600976 | 0.77 | CHRM2 (0.52) | MEN1KMT2ATSHRALDH1A1CYP19A1 | |
| SCHEMBL8283898 | 0.76 | GAA (0.39) | PIK3CDMEN1KMT2ATSHRGAA | |
| SCHEMBL8294610 | 0.75 | PIK3CD (0.39) | PIK3CDMEN1KMT2ATSHRGAA | |
| SCHEMBL8282191 | 0.74 | KDM4E (0.45) | PIK3CDMEN1KMT2ATSHRGAA | |
| SCHEMBL8283007 | 0.73 | CHRM2 (0.41) | MEN1KMT2ATSHRALDH1A1CYP19A1 | |
| SCHEMBL8282203 | 0.73 | PIK3CD (0.38) | PIK3CDGAAALDH1A1CYP19A1CASP6 | |
| SCHEMBL8283572 | 0.73 | MEN1 (0.38) | PIK3CDMEN1KMT2ATSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022180-B1 | UV ABSORBING COMPOUNDS, COMPOSITIONS COMPRISING SAME AND USES THEREOF | CORAL SUNSCREEN PTY LTD (AU) | 2022-02-23 | — | — | EP | disclosed |
| US-20180155288-A1 | UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof | CORAL SUNSCREEN PTY LTD (AU) | 2018-06-07 | — | — | US | disclosed |
| US-9920009-B2 | UV absorbing compounds, compositions comprising same and uses thereof | CORAL SUNSCREEN PTY LTD (AU) | 2018-03-20 | — | — | US | disclosed |
| US-20160244409-A1 | UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof | CORAL SUNSCREEN PTY LTD (AU) | 2016-08-25 | — | — | US | disclosed |
| EP-3022180-A1 | UV ABSORBING COMPOUNDS, COMPOSITIONS COMPRISING SAME AND USES THEREOF | Coral Sunscreen Pty Ltd (AU) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015006803-A1 | UV ABSORBING COMPOUNDS, COMPOSITIONS COMPRISING SAME AND USES THEREOF | CORAL SUNSCREEN PTY LTD (AU) | 2015-01-22 | — | — | WO | disclosed |
| EP-1730142-B1 | NOVEL KETOAMIDES WITH CYCLIC P4'S AS INHIBITORS OF NS3 SERINE PROTEASE OF HEPATITIS C VIRUS | SCHERING CORP (US) | 2011-06-29 | — | — | EP | disclosed |
| US-7619094-B2 | Ketoamides with cyclic P4's as inhibitors of NS3 serine protease of hepatitis C virus | SCHERING CORPORATION (US) | 2009-11-17 | — | — | US | disclosed |
| US-7619094-B2 | Ketoamides with cyclic P4's as inhibitors of NS3 serine protease of hepatitis C virus | SCHERING CORPORATION (US) | 2009-11-17 | — | — | US | disclosed |
| US-7449447-B2 | Peptidomimetic NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2008-11-11 | — | — | US | disclosed |
| US-20070093430-A1 | Novel ketoamides with cyclic P4's as inhibitors of NS3 serine protease of hepatitis C virus | MERCK SHARP & DOHME CORP. | 2007-04-26 | — | — | US | disclosed |
| US-20070093430-A1 | Novel ketoamides with cyclic P4's as inhibitors of NS3 serine protease of hepatitis C virus | MERCK SHARP & DOHME CORP. | 2007-04-26 | — | — | US | disclosed |
| US-7173057-B2 | Ketoamides with cyclic P4'S as inhibitors of NS3 protease of hepatitis C virus | SCHERING CORPORATION (US) | 2007-02-06 | — | — | US | disclosed |
| US-7173057-B2 | Ketoamides with cyclic P4'S as inhibitors of NS3 protease of hepatitis C virus | SCHERING CORPORATION (US) | 2007-02-06 | — | — | US | disclosed |
| WO-2005085242-A1 | NOVEL KETOAMIDES WITH CYCLIC P4'S AS INHIBITORS OF NS3 SERINE PROTEASE OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2005-09-15 | — | — | WO | disclosed |
| WO-2005021584-A2 | NOVEL PEPTIDOMIMETIC NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2005-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180155288-A1 | UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof | ERCC1, ERCC4, ERCC5 | PIK3CD 4199/4885MEN1 395/4885KMT2A 1668/4885 |
| US-20160244409-A1 | UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof | ERCC4, ERCC1, ERCC5 | PIK3CD 3570/4885MEN1 1260/4885KMT2A 1490/4885 |
| US-20070093430-A1 | Novel ketoamides with cyclic P4's as inhibitors of NS3 serine protease of hepatitis C virus | PREP, PRSS1, P4HB | PIK3CD 850/4885MEN1 4705/4885KMT2A 1104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.