SCHEMBL828236

SCHEMBL828236

CCOCOC(=O)C=CC#N

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.39
ATM Q13315 1/20 0.35
ALDH1A1 P00352 4/20 0.33
TSHR P16473 2/20 0.33
MAPT P10636 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
CYP2C9 P11712 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4889833 0.85 HCAR2 (0.43) HCAR2ATMTSHRMAPTZDHHC20
SCHEMBL29446 0.84
SCHEMBL600328 0.84
SCHEMBL442803 0.84
SCHEMBL10395587 0.83 HCAR2 (0.54) HCAR2ATMALDH1A1TSHRMAPT
SCHEMBL462001 0.83 TSHR (0.48) HCAR2ATMALDH1A1TSHRMAPT
SCHEMBL4892555 0.82 ATM (0.52) HCAR2ATMALDH1A1TSHRMAPT
SCHEMBL4889687 0.81 TSHR (0.47) HCAR2ATMALDH1A1TSHRMAPT
SCHEMBL4888147 0.80 ATM (0.48) HCAR2ATMALDH1A1TSHRMAPT
SCHEMBL5555666 0.80 HCAR2 (0.33) HCAR2ATMZDHHC20ZDHHC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142657-B2 Insertion-point seal for spiral wound module DOW GLOBAL TECHNOLOGIES LLC (US) 2012-03-27 US claimed
US-20110174429-A1 INSERTION-POINT SEAL FOR SPIRAL WOUND MODULE FILMTEC CORPORATION 2011-07-21 US claimed
EP-1971421-B1 INSERTION-POINT SEAL FOR SPIRAL WOUND MODULE DOW GLOBAL TECHNOLOGIES LLC (US) 2011-07-06 EP claimed
US-7951295-B2 Insertion-point seal for spiral wound module DOW GLOBAL TECHNOLOGIES LLC (US) 2011-05-31 US claimed
US-20110049043-A1 INSERTION-POINT SEAL FOR SPIRAL WOUND MODULE FILMTEC CORPORATION 2011-03-03 US claimed
EP-1971421-A1 INSERTION-POINT SEAL FOR SPIRAL WOUND MODULE DOW GLOBAL TECHNOLOGIES INC. (US) 2008-09-24 EP claimed
WO-2007067751-A1 INSERTION-POINT SEAL FOR SPIRAL WOUND MODULE DOW GLOBAL TECHNOLOGIES INC. (US) 2007-06-14 WO claimed
US-20040013614-A1 Acrylic-based adhesive composition BTG INTERNATIONAL LIMITED (GB) 2004-01-22 US claimed
EP-1341563-A1 ACRYLIC-BASED ADHESIVE COMPOSITION UNIVERSIDAD DE ALICANTE (ES) 2003-09-10 EP claimed
WO-2002009784-A1 ACRYLIC-BASED ADHESIVE COMPOSITION UNIVERSIDAD DE ALICANTE (ES) 2002-02-07 WO claimed
US-20230364304-A1 METHODS OF FORMING BONE INTERFACE SCAFFOLDS Sparta Biopharma LLC (US) 2023-11-16 US disclosed
CN-114796591-A Cyanoacrylate medical adhesive and preparation method and application thereof 北京康派特医疗器械有限公司 2022-07-29 CN disclosed
US-11364324-B2 Methods of forming bone interface scaffolds SPARTA BIOPHARMA INC. (US) 2022-06-21 US disclosed
WO-2022046701-A1 METHODS OF FORMING BONE INTERFACE SCAFFOLDS Sparta Biopharma LLC (US) 2022-03-03 WO disclosed
US-20220054709-A1 METHODS OF FORMING BONE INTERFACE SCAFFOLDS SPARTA BIOPHARMA INC. 2022-02-24 US disclosed
EP-1971421-A1 INSERTION-POINT SEAL FOR SPIRAL WOUND MODULE DOW GLOBAL TECHNOLOGIES INC. (US) 2008-09-24 EP disclosed
WO-2007067751-A1 INSERTION-POINT SEAL FOR SPIRAL WOUND MODULE DOW GLOBAL TECHNOLOGIES INC. (US) 2007-06-14 WO disclosed
US-20040013614-A1 Acrylic-based adhesive composition BTG INTERNATIONAL LIMITED (GB) 2004-01-22 US disclosed
EP-1341563-A1 ACRYLIC-BASED ADHESIVE COMPOSITION UNIVERSIDAD DE ALICANTE (ES) 2003-09-10 EP disclosed
WO-2002009784-A1 ACRYLIC-BASED ADHESIVE COMPOSITION UNIVERSIDAD DE ALICANTE (ES) 2002-02-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040013614-A1 Acrylic-based adhesive composition C5AR1, C1R, COL2A1 HCAR2 110/4885ATM 729/4885ALDH1A1 980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.