Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.48 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1149383 | 0.90 | ALDH1A1 (0.60) | ALDH1A1RAB9AGAAKMT2ABAZ2B | |
| SCHEMBL1149919 | 0.87 | ALDH1A1 (0.57) | ALDH1A1RAB9AGAAKMT2ABAZ2B | |
| SCHEMBL1149247 | 0.87 | ALDH1A1 (0.57) | ALDH1A1RAB9AGAAKMT2ABAZ2B | |
| SCHEMBL1149554 | 0.87 | RAB9A (0.66) | ALDH1A1RAB9AGAAKMT2ABAZ2B | |
| SCHEMBL1149220 | 0.87 | ALDH1A1 (0.76) | ALDH1A1RAB9AGAAKMT2ABAZ2B | |
| SCHEMBL1149275 | 0.82 | ALDH1A1 (0.52) | ALDH1A1RAB9AGAAKMT2ABAZ2B | |
| SCHEMBL1149721 | 0.81 | ALDH1A1 (0.57) | ALDH1A1RAB9AGAAKMT2ABAZ2B | |
| SCHEMBL1149361 | 0.81 | ALDH1A1 (0.60) | ALDH1A1RAB9AGAAKMT2ABAZ2B | |
| SCHEMBL12704185 | 0.81 | ALDH1A1 (0.52) | ALDH1A1RAB9AGAAKMT2ABAZ2B | |
| SCHEMBL13625702 | 0.78 | ALDH1A1 (0.59) | ALDH1A1RAB9AGAAKMT2ABAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005066135-A2 | PYRROLE AND PYRAZOLE DAAO INHIBITORS | SEPRACOR INC. (US) | 2005-07-21 | — | — | WO | disclosed |