Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.48 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1149383 | 0.90 | ALDH1A1 (0.60) | RAB9AALDH1A1ALOX15NPC1L3MBTL1 | |
| SCHEMBL12704185 | 0.88 | ALDH1A1 (0.52) | RAB9AALDH1A1ALOX15NPC1HTT | |
| SCHEMBL1149275 | 0.88 | ALDH1A1 (0.52) | RAB9AALDH1A1ALOX15NPC1GAA | |
| SCHEMBL8283442 | 0.87 | ALDH1A1 (0.57) | RAB9AALDH1A1ALOX15HTTGAA | |
| SCHEMBL1149919 | 0.87 | ALDH1A1 (0.57) | RAB9AALDH1A1ALOX15HTTGAA | |
| SCHEMBL1149247 | 0.87 | ALDH1A1 (0.57) | RAB9AALDH1A1ALOX15NPC1HTT | |
| SCHEMBL1149220 | 0.87 | ALDH1A1 (0.76) | RAB9AALDH1A1ALOX15GAALMNA | |
| SCHEMBL1149829 | 0.84 | ALDH1A1 (0.46) | RAB9AALDH1A1ALOX15NPC1HTT | |
| SCHEMBL1149721 | 0.81 | ALDH1A1 (0.57) | RAB9AALDH1A1NPC1GAALMNA | |
| SCHEMBL1149361 | 0.81 | ALDH1A1 (0.60) | RAB9AALDH1A1L3MBTL1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111479806-B | D-amino acid oxidase inhibitors and therapeutic uses thereof | 心悦生医股份有限公司 | 2024-01-30 | — | — | CN | disclosed |
| US-11753400-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-09-12 | — | — | US | disclosed |
| US-11753400-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-09-12 | — | — | US | disclosed |
| US-11753400-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-09-12 | — | — | US | disclosed |
| US-20200331894-A1 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2020-10-22 | — | — | US | disclosed |
| US-20200331894-A1 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2020-10-22 | — | — | US | disclosed |
| CN-111479806-A | D-amino acid oxidase inhibitors and therapeutic uses thereof | 心悦生医股份有限公司 | 2020-07-31 | — | — | CN | disclosed |
| WO-2019076329-A9 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | TSAI GUOCHUAN EMIL (CN) | 2019-08-15 | — | — | WO | disclosed |
| US-10336724-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2019-07-02 | — | — | US | disclosed |
| US-10336724-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2019-07-02 | — | — | US | disclosed |
| US-20090170916-A1 | Pyrrole and Pyrazole DAAO Inhibitors | SEPRACOR INC. (US) | 2009-07-02 | — | — | US | disclosed |
| US-20090170916-A1 | Pyrrole and Pyrazole DAAO Inhibitors | SEPRACOR INC. (US) | 2009-07-02 | — | — | US | disclosed |
| US-20090170916-A1 | Pyrrole and Pyrazole DAAO Inhibitors | SEPRACOR INC. (US) | 2009-07-02 | — | — | US | disclosed |
| US-7488747-B2 | Pyrrole and pyrazole DAAO inhibitors | SEPRACOR INC. (US) | 2009-02-10 | — | — | US | disclosed |
| US-7488747-B2 | Pyrrole and pyrazole DAAO inhibitors | SEPRACOR INC. (US) | 2009-02-10 | — | — | US | disclosed |
| US-7488747-B2 | Pyrrole and pyrazole DAAO inhibitors | SEPRACOR INC. (US) | 2009-02-10 | — | — | US | disclosed |
| EP-1709004-A2 | PYRROLE AND PYRAZOLE DAAO INHIBITORS | Sepracor Inc. (US) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005066135-A2 | PYRROLE AND PYRAZOLE DAAO INHIBITORS | SEPRACOR INC. (US) | 2005-07-21 | — | — | WO | disclosed |
| WO-2005066135-A2 | PYRROLE AND PYRAZOLE DAAO INHIBITORS | SEPRACOR INC. (US) | 2005-07-21 | — | — | WO | disclosed |
| US-20050143443-A1 | Pyrrole and pyrazole DAAO inhibitors | SEPRACOR INC. (US) | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331894-A1 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | DAO, DDO, DDC | RAB9A 2735/4885ALDH1A1 243/4885ALOX15 200/4885 |
| US-20050143443-A1 | Pyrrole and pyrazole DAAO inhibitors | DDO, DAO, SRR | RAB9A 2111/4885ALDH1A1 3634/4885ALOX15 36/4885 |
| US-11753400-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | DAO, DDO, DDC | RAB9A 2735/4885ALDH1A1 243/4885ALOX15 200/4885 |
| US-10336724-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | DAO, DDO, DDC | RAB9A 2735/4885ALDH1A1 243/4885ALOX15 200/4885 |
| US-20090170916-A1 | Pyrrole and Pyrazole DAAO Inhibitors | DDO, DAO, SRR | RAB9A 2111/4885ALDH1A1 3634/4885ALOX15 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.