Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | ANPEP | P15144 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3068204 | 1.00 | MMP2 (0.46) | MMP2ANPEPCYP1A2POLBCYP3A4 | |
| SCHEMBL29689646 | 1.00 | MMP2 (0.46) | MMP2ANPEPCYP1A2POLBCYP3A4 | |
| SCHEMBL16350377 | 1.00 | MMP2 (0.46) | MMP2ANPEPCYP1A2POLBCYP3A4 | |
| SCHEMBL4458704 | 1.00 | MMP2 (0.46) | MMP2ANPEPCYP1A2POLBCYP3A4 | |
| SCHEMBL29689527 | 0.88 | FKBP1A (0.42) | CYP1A2POLBCYP3A4CYP2C19FKBP1A | |
| SCHEMBL22602098 | 0.88 | FKBP1A (0.42) | CYP1A2POLBCYP3A4CYP2C19FKBP1A | |
| SCHEMBL29214257 | 0.88 | FKBP1A (0.42) | CYP1A2POLBCYP3A4CYP2C19FKBP1A | |
| SCHEMBL2202494 | 0.87 | POLB (0.50) | CYP1A2POLBCYP3A4CYP2C19FKBP1A | |
| SCHEMBL116396 | 0.87 | POLB (0.50) | CYP1A2POLBCYP3A4CYP2C19FKBP1A | |
| SCHEMBL3041685 | 0.87 | POLB (0.50) | CYP1A2POLBCYP3A4CYP2C19FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005070919-A1 | N-TYPE CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD. (CA) | 2005-08-04 | — | — | WO | disclosed |