Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | C1R | P00736 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL828190 | 0.85 | FFAR1 (0.39) | FFAR1PDE10AABL1CYP3A4CYP2C9 | |
| SCHEMBL826935 | 0.79 | FFAR1 (0.44) | FFAR1PDE10AALDH1A1C1RPIK3C3 | |
| SCHEMBL826952 | 0.79 | FFAR1 (0.46) | FFAR1PDE10AALDH1A1C1RPIK3C3 | |
| SCHEMBL828994 | 0.79 | FFAR1 (0.41) | FFAR1PDE10AALDH1A1C1RPIK3C3 | |
| SCHEMBL827287 | 0.78 | FFAR1 (0.43) | FFAR1PDE10AALDH1A1C1RPIK3C3 | |
| SCHEMBL827900 | 0.78 | FFAR1 (0.43) | FFAR1PDE10AALDH1A1C1RPIK3C3 | |
| SCHEMBL827978 | 0.78 | FFAR1 (0.42) | FFAR1PDE10AALDH1A1C1RPIK3C3 | |
| SCHEMBL828396 | 0.77 | FFAR1 (0.41) | FFAR1PDE10AC1RPIK3C3KMT2A | |
| SCHEMBL828548 | 0.77 | FFAR1 (0.42) | FFAR1PDE10AALDH1A1C1RPIK3C3 | |
| SCHEMBL828049 | 0.77 | FFAR1 (0.42) | FFAR1PDE10AALDH1A1C1RPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143274-B2 | 1-(2H)-isoquinolone derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2012-03-27 | — | — | US | disclosed |