Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.48 |
| ▸ | HTR1A | P08908 | 6/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN4A | P35499 | 1/20 | 0.42 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499192 | 0.90 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3HTR1AMAOB | |
| SCHEMBL8285825 | 0.81 | REN (0.47) | SLC6A2SLC6A4SLC6A3HTR1AMAOB | |
| SCHEMBL8498628 | 0.79 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3HTR1AMAOB | |
| SCHEMBL8286499 | 0.79 | HTR1A (0.49) | SLC6A2SLC6A4SLC6A3HTR1AMAOB | |
| SCHEMBL12420864 | 0.77 | HRH1 (0.54) | SLC6A2SLC6A4SLC6A3HTR1AMAOB | |
| SCHEMBL8492021 | 0.76 | SLC18A3 (0.59) | SLC6A2SLC6A4SLC6A3HTR1AMAOB | |
| SCHEMBL8484170 | 0.74 | HTR1A (0.54) | SLC6A2SLC6A4SLC6A3HTR1AKCNH2 | |
| SCHEMBL23250045 | 0.74 | KCNH2 (0.42) | KCNH2SLC18A3SIGMAR1PRMT5WDR77 | |
| SCHEMBL8284788 | 0.73 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3SLC18A3SIGMAR1 | |
| SCHEMBL10273172 | 0.73 | MAOB (0.58) | SLC6A2SLC6A4SLC6A3HTR1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1707202-A1 | Organic compounds | Speedel Experimenta AG (CH) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005061457-A1 | ORGANIC COMPOUNDS | SPEEDEL EXPERIMENTA AG (CH) | 2005-07-07 | — | — | WO | disclosed |