Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | DRD5 | P21918 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484603 | 0.90 | HTR1A (0.45) | HTR1ADRD2DRD1DRD5HTR2A | |
| SCHEMBL8284777 | 0.87 | HTR1A (0.46) | HTR1ADRD2DRD1DRD5HTR2A | |
| SCHEMBL8484380 | 0.87 | SLC6A2 (0.47) | HTR1ADRD2DRD1DRD5HTR2A | |
| SCHEMBL8286499 | 0.86 | HTR1A (0.49) | HTR1ADRD2DRD1DRD5HTR2A | |
| SCHEMBL8490062 | 0.86 | SLC6A2 (0.57) | HTR1ADRD2DRD1DRD5HTR2A | |
| SCHEMBL8492021 | 0.86 | SLC18A3 (0.59) | HTR1ASLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL8285669 | 0.85 | SLC6A2 (0.60) | HTR1ASLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL8234772 | 0.84 | HTR2C (0.45) | HTR2CKCNH2HRH3SLC18A3SIGMAR1 | |
| SCHEMBL11832143 | 0.84 | MAOA (0.55) | HTR2CKCNH2HRH3SLC18A3SIGMAR1 | |
| SCHEMBL8285825 | 0.84 | REN (0.47) | HTR1ADRD2DRD1DRD5HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1707202-A1 | Organic compounds | Speedel Experimenta AG (CH) | 2006-10-04 | — | — | EP | disclosed |