Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | TET3 | O43151 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | ASPH | Q12797 | 1/20 | 0.31 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6840488 | 0.80 | KDM4E (0.55) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16139802 | 0.78 | KDM4E (0.53) | KDM4EMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL13593104 | 0.78 | KDM4E (0.53) | KDM4EMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL19615659 | 0.76 | KDM4E (0.50) | KDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL19632068 | 0.76 | KDM4E (0.50) | KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19615702 | 0.76 | KDM4E (0.50) | KDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9243795 | 0.74 | KDM4E (0.49) | KDM4EMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL19631996 | 0.74 | KDM4E (0.49) | KDM4EMAPTKDM4C | |
| SCHEMBL8570227 | 0.74 | KDM4E (0.49) | KDM4EMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL19632024 | 0.74 | KDM4E (0.49) | KDM4ERAB9ASMN1; SMN2ALDH1A1KDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061450-A2 | HIV PROTEASE INHIBITING SULFONAMIDES | ABBOTT LABORATORIES (US) | 2005-07-07 | — | — | WO | disclosed |