Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344177 | 1.00 | KDM4E (0.49) | KDM4ENOS3NOS2KMT2APOLB | |
| SCHEMBL9243795 | 1.00 | KDM4E (0.49) | KDM4ENOS3NOS2KMT2APOLB | |
| SCHEMBL19632011 | 0.85 | KDM4E (0.45) | KDM4ENOS3NOS2KMT2APOLB | |
| Hydrochloric Acid SCHEMBL19615616 | 0.84 | KDM4E (0.44) | KDM4ENOS3NOS2KMT2APOLB | |
| Hydrochloric Acid SCHEMBL19615617 | 0.84 | KDM4E (0.44) | KDM4ENOS3NOS2KMT2APOLB | |
| SCHEMBL1991324 | 0.82 | NOS3 (0.52) | KDM4ENOS3NOS2KMT2APOLB | |
| SCHEMBL3719130 | 0.79 | NOS3 (0.46) | NOS3NOS2KMT2AADRB2DDR1 | |
| SCHEMBL12446917 | 0.79 | NOS3 (0.50) | NOS3NOS2KMT2APOLBADRB2 | |
| SCHEMBL13847246 | 0.79 | NOS3 (0.50) | NOS3NOS2KMT2APOLBADRB2 | |
| SCHEMBL2337914 | 0.79 | NOS3 (0.50) | NOS3NOS2KMT2APOLBADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357152-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS VIII | BASF SE (DE) | 2023-11-09 | — | — | US | disclosed |
| CN-116056576-A | Use of strobilurin type compounds for combating phytopathogenic fungi containing F129L amino acid substitutions conferring tolerance to Qo inhibitor VIII in mitochondrial cytochrome b proteins | 巴斯夫欧洲公司 | 2023-05-02 | — | — | CN | disclosed |
| WO-1999011129-A1 | ENANTIOMERICALLY ENRICHED COMPOSITIONS AND THEIR PESTICIDAL USE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-03-11 | — | — | WO | disclosed |
| EP-0586393-B1 | SUBSTITUTED-2-PHENYL-3-METHOXYPROPENOATES AS FUNGICIDES | ZENECA LTD (GB) | 1998-06-17 | — | — | EP | disclosed |
| US-5439910-A | For applying to plants, seeds or soils | ZENECA LIMITED (GB) | 1995-08-08 | — | — | US | disclosed |
| EP-0586393-A1 | SUBSTITUTED-2-PHENYL-3-METHOXYPROPENOATES AS FUNGICIDES | ZENECA LIMITED (GB) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992018487-A1 | SUBSTITUTED-2-PHENYL-3-METHOXYPROPENOATES AS FUNGICIDES | ZENECA LIMITED (GB) | 1992-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357152-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS VIII | COX5B, COX6B1, SQOR | KDM4E 2949/4885NOS3 1911/4885NOS2 1361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.