Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL953002 | 0.73 | CES1 (0.39) | CES2CES1HTTRECQLLMNA | |
| SCHEMBL15841309 | 0.71 | — | — | |
| SCHEMBL317184 | 0.67 | CES2 (0.43) | CES2CES1HTTRECQLLMNA | |
| SCHEMBL6448128 | 0.67 | CES2 (0.43) | CES2CES1HTTRECQLLMNA | |
| SCHEMBL6140455 | 0.66 | SMN1; SMN2 (0.38) | CES2CES1HTT | |
| SCHEMBL826794 | 0.65 | CES2 (0.35) | CES2CES1HTT | |
| SCHEMBL7783591 | 0.65 | CES2 (0.35) | CES2CES1HTT | |
| SCHEMBL25142234 | 0.64 | HTT (0.43) | HTTRECQLLMNATP53MAPK1 | |
| SCHEMBL10937999 | 0.64 | SMN1; SMN2 (0.41) | CES2CES1HTT | |
| SCHEMBL31542027 | 0.63 | SMN1; SMN2 (0.41) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436199-B2 | Strong boron-containing acids, the preparation and use thereof | MERCK PATENT GMBH (DE) | 2013-05-07 | — | — | US | disclosed |
| US-8143452-B2 | Salts having alkoxytris(fluoroalkyl)borate anions | MERCK PATENT GMBH (DE) | 2012-03-27 | — | — | US | disclosed |
| EP-1802638-B1 | BORON-CONTAINING SALTS, THE PRODUCTION THEREOF AND THEIR USE | MERCK PATENT GMBH (DE) | 2011-07-20 | — | — | EP | disclosed |
| US-20100160689-A1 | SALTS HAVING ALKOXYTRIS(FLUOROALKYL)BORATE ANIONS | IGNATYEV NIKOLA MYKOLA | 2010-06-24 | — | — | US | disclosed |
| US-7700781-B2 | Salts having alkoxytris(fluoroalkyl)borate anions | MERCK PATENT GMBH (DE) | 2010-04-20 | — | — | US | disclosed |
| US-20100069655-A1 | NOVEL STRONG BORON-CONTAINING ACIDS, THE PREPARATION AND USE THEREOF | FINZE MAIK | 2010-03-18 | — | — | US | disclosed |
| EP-1773848-B1 | SALTS CONTAINING ALKOXYTRIS (FLUOROALKYL) BORATE ANIONS | MERCK PATENT GMBH (DE) | 2009-12-30 | — | — | EP | disclosed |
| US-20080214829-A1 | Salts Having Alkoxytris(Fluoroalkyl)Borate Anions | MERCK PATENT GMBH (DE) | 2008-09-04 | — | — | US | disclosed |
| US-20070293391-A1 | Novel Strong Boron-Containing Acids, The Preparation And Use Thereof | MERCK PATENT GMBH (DE) | 2007-12-20 | — | — | US | disclosed |
| EP-1802638-A1 | NOVEL BORON-CONTAINING STRONG ACIDS, THE PRODUCTION THEREOF AND THEIR USE | Merck Patent GmbH (DE) | 2007-07-04 | — | — | EP | disclosed |
| EP-1773848-A2 | SALTS CONTAINING ALKOXYTRIS (FLUOROALKYL) BORATE ANIONS | Merck Patent GmbH (DE) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006045405-A1 | NOVEL BORON-CONTAINING STRONG ACIDS, THE PRODUCTION THEREOF AND THEIR USE | MERCK PATENT GMBH (DE) | 2006-05-04 | — | — | WO | disclosed |
| WO-2006010455-A2 | SALTS CONTAINING ALKOXYTRIS (FLUOROALKYL) BORATE ANIONS | MERCK PATENT GMBH (DE) | 2006-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214829-A1 | Salts Having Alkoxytris(Fluoroalkyl)Borate Anions | ALK, CCL11, ALKBH3 | CES2 2127/4885CES1 3156/4885HTT 1813/4885 |
| US-20070293391-A1 | Novel Strong Boron-Containing Acids, The Preparation And Use Thereof | AFF4, AFF1, AFF2 | CES2 2110/4885CES1 1713/4885HTT 3118/4885 |
| US-20100069655-A1 | NOVEL STRONG BORON-CONTAINING ACIDS, THE PREPARATION AND USE THEREOF | AFF4, AFF1, AFF2 | CES2 2009/4885CES1 1655/4885HTT 3688/4885 |
| US-20100160689-A1 | SALTS HAVING ALKOXYTRIS(FLUOROALKYL)BORATE ANIONS | ALK, CCL11, ALKBH3 | CES2 2127/4885CES1 3156/4885HTT 1813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.