Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1900629 | 0.96 | CES2 (0.39) | CES2CES1HTTLMNATP53 | |
| SCHEMBL6448128 | 0.93 | CES2 (0.43) | CES2CES1HTTLMNATP53 | |
| SCHEMBL9748198 | 0.84 | TAS1R3 (0.44) | CES2CES1HTTPKMSMN1; SMN2 | |
| SCHEMBL9320500 | 0.82 | CES2 (0.32) | CES2CES1HTT | |
| SCHEMBL10937999 | 0.80 | SMN1; SMN2 (0.41) | CES2CES1HTTSMN1; SMN2TSHR | |
| SCHEMBL11255943 | 0.80 | CES2 (0.52) | CES2CES1HTTLMNATP53 | |
| SCHEMBL10709506 | 0.80 | CES2 (0.46) | CES2CES1 | |
| SCHEMBL10710744 | 0.78 | CES2 (0.56) | CES2CES1HTTCA1CA2 | |
| SCHEMBL9073432 | 0.78 | SMN1; SMN2 (0.44) | CES2CES1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL11263582 | 0.78 | CES2 (0.56) | CES2CES1HTTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217897-A | Polyelectrolyte material, preparation method thereof and cation selective separation membrane | 中国科学技术大学 | 2023-06-06 | — | — | CN | claimed |
| US-11596716-B2 | Compounds and matrices for use in bone growth and repair | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2023-03-07 | — | — | US | claimed |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2021-05-13 | — | — | US | claimed |
| EP-3038621-A2 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | Human Biomolecular Research Institute (US) | 2016-07-06 | — | — | EP | claimed |
| US-20160038641-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2016-02-11 | — | — | US | claimed |
| WO-2014146039-A2 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2014-09-18 | — | — | WO | claimed |
| WO-2025132776-A1 | USE OF IRON-BASED COMPOUNDS FOR THE SYNTHESIS OF BORATED COMPOUNDS, AND CORRESPONDING METHODS | Universite Paris-Saclay (FR) | 2025-06-26 | — | — | WO | disclosed |
| EP-4543895-A1 | NOVEL IRON-BASED COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF, AND USE THEREOF AS CATALYSTS | Université Paris-Saclay (FR) | 2025-04-30 | — | — | EP | disclosed |
| CN-119816509-A | Novel iron-based compounds, method for the production thereof and use thereof as catalysts | 巴黎萨克雷大学 | 2025-04-11 | — | — | CN | disclosed |
| US-11977084-B2 | Nervous system-specific transmembrane proteasome complex that modulates neuronal signaling through extracellular signaling via brain activity peptides | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-05-07 | — | — | US | disclosed |
| WO-2023247697-A1 | NOVEL IRON-BASED COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF, AND USE THEREOF AS CATALYSTS | Universite Paris-Saclay (FR) | 2023-12-28 | — | — | WO | disclosed |
| WO-2023227577-A1 | HYDROPHILIC COATINGS FOR VASCULAR MEDICAL PRODUCTS | BIOTRONIK AG (CH) | 2023-11-30 | — | — | WO | disclosed |
| CN-116217897-A | Polyelectrolyte material, preparation method thereof and cation selective separation membrane | 中国科学技术大学 | 2023-06-06 | — | — | CN | disclosed |
| EP-0067851-A4 | FLUORINATED MONOPHENOLS AND DIPHENOLS AND METHOD FOR THEIR PREPARATION. | GEN ELECTRIC (US) | 1983-06-09 | — | — | EP | disclosed |
| EP-0067851-A1 | FLUORINATED MONOPHENOLS AND DIPHENOLS AND METHOD FOR THEIR PREPARATION | GENERAL ELECTRIC COMPANY (US) | 1982-12-29 | — | — | EP | disclosed |
| US-4358624-A | FLUOROPOLYMERS; POLYCARBONATES; FIREPROOFING | GENERAL ELECTRIC COMPANY (US) | 1982-11-09 | — | — | US | disclosed |
| WO-1982002380-A1 | FLUORINATED MONOPHENOLS AND DIPHENOLS AND METHOD FOR THEIR PREPARATION | GEN ELECTRIC (US) | 1982-07-22 | — | — | WO | disclosed |
| EP-0023647-B1 | Process for the preparation of halogenated benzoyl fluorides | BAYER AG (DE) | 1982-06-30 | — | — | EP | disclosed |
| US-4330366-A | Process for the preparation of halogenated benzoyl fluorides | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-18 | — | — | US | disclosed |
| EP-0023647-A1 | Process for the preparation of halogenated benzoyl fluorides | BAYER AG (DE) | 1981-02-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11596716-B2 | Compounds and matrices for use in bone growth and repair | BMP2, BMP4, BMP6 | CES2 4108/4885CES1 4462/4885HTT 4875/4885 |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | BMP2, BMP4, BMP6 | CES2 4108/4885CES1 4462/4885HTT 4875/4885 |
| US-20160038641-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | BMP2, BMP4, BMP6 | CES2 4063/4885CES1 4830/4885HTT 4884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.