Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14002878 | 0.85 | FFAR4 (0.47) | CYP3A4TSHRRECQLFFAR4 | |
| SCHEMBL776364 | 0.80 | RAPGEF4 (0.55) | CYP3A4TSHRRECQLFFAR4 | |
| Hydrochloric Acid SCHEMBL27516695 | 0.78 | RAPGEF4 (0.52) | CYP3A4TSHRRECQLFFAR4 | |
| SCHEMBL8285545 | 0.77 | TAAR1 (0.44) | TAAR1CYP1A2CYP2A6HTR2ACYP3A4 | |
| SCHEMBL13633349 | 0.77 | TAAR1 (0.41) | TAAR1CYP1A2CYP2A6HTR2AHTR2C | |
| SCHEMBL14007683 | 0.75 | MEN1 (0.42) | CYP3A4TSHRRECQLFFAR4 | |
| SCHEMBL13984313 | 0.73 | TAAR1 (0.50) | TAAR1CYP1A2CYP2A6HTR2AHTR2C | |
| SCHEMBL12852100 | 0.71 | ALDH1A1 (0.43) | CYP3A4TSHRRECQL | |
| SCHEMBL15262016 | 0.71 | TAAR1 (0.44) | TAAR1CYP1A2CYP2A6HTR2AHTR2C | |
| SCHEMBL9702752 | 0.71 | PTGS1 (0.53) | TAAR1CYP1A2CYP2A6RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058871-A1 | MORPHOLINYL CONTAINING BENZIMIDAZOLES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-06-30 | — | — | WO | disclosed |