Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22542358 | 0.82 | PIK3CD (0.45) | MTNR1AMTNR1BRPS6KA2MAPTGAA | |
| SCHEMBL8280423 | 0.80 | RPS6KA2 (0.46) | RPS6KA2SLC2A1AOC3ALDH1A1CA12 | |
| SCHEMBL13358132 | 0.78 | HTT (0.43) | MTNR1AMTNR1BALDH1A1CA12CA2 | |
| SCHEMBL8338453 | 0.77 | PYCR1 (0.51) | MAPTAOC3SMN1; SMN2ALDH1A1CHRM2 | |
| SCHEMBL14149521 | 0.77 | MAPT (0.53) | MTNR1AMTNR1BRPS6KA2MAPTSLC2A1 | |
| SCHEMBL22015434 | 0.76 | ALDH1A1 (0.47) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4745147 | 0.75 | CA1 (0.50) | RPS6KA2MAPTGAASLC2A1AOC3 | |
| SCHEMBL13261439 | 0.75 | MAPT (0.47) | RPS6KA2MAPTSLC2A1AOC3ALDH1A1 | |
| 1,4-Dimethoxybenzene SCHEMBL10989906 | 0.74 | CA1 (0.61) | MAPTGAANPC1RAB9AALDH1A1 | |
| SCHEMBL22542360 | 0.74 | TAAR1 (0.48) | RPS6KA2SLC2A1AOC3ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058884-A2 | CYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2005-06-30 | — | — | WO | disclosed |