SCHEMBL4745147

SCHEMBL4745147

CCN(C)c1ccc(OC)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA12 O43570 1/20 0.50
CA14 Q9ULX7 1/20 0.50
RPS6KA2 Q15349 1/20 0.49
SLC2A1 P11166 1/20 0.48
ADRA2A P08913 1/20 0.46
ADRA2B P18089 1/20 0.46
ADRA2C P18825 1/20 0.46
AOC3 Q16853 2/20 0.44
APP P05067 1/20 0.44
NR1I2 O75469 1/20 0.43
MAPT P10636 3/20 0.42
ALDH1A1 P00352 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MAPK1 P28482 2/20 0.42
GAA P10253 1/20 0.42
GFER P55789 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3654830 0.98 CA12 (0.48) CA1CA2CA7CA9CA12
SCHEMBL17228668 0.89 ADRA2A (0.50) CA1CA2CA7CA9CA12
SCHEMBL8280423 0.83 RPS6KA2 (0.46) CA1CA2CA7CA9CA12
SCHEMBL10330355 0.83 ADRA2A (0.58) ADRA2AADRA2BADRA2CMAPTALDH1A1
SCHEMBL5541675 0.80 CA1 (0.48) CA1CA2CA7CA9CA12
SCHEMBL14149521 0.79 MAPT (0.53) CA1CA2CA7CA9CA12
SCHEMBL24247974 0.79 CA1 (0.52) CA1CA2CA7CA9CA12
SCHEMBL1263095 0.79 ALDH1A1 (0.60) CA1CA2CA7CA9CA12
SCHEMBL19302284 0.78 PYCR1 (0.53) CA1CA2CA7CA9CA12
SCHEMBL21600871 0.78 KDM4E (0.42) ADRA2AADRA2BADRA2CAPPMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119040223-B Lactobacillus rhamnosus RH22 with anti-inflammatory and antiallergic effects and application thereof 微康益生菌(苏州)股份有限公司 2025-02-28 CN disclosed
CN-119040223-A Lactobacillus rhamnosus RH22 with anti-inflammatory and antiallergic effects and application thereof 微康益生菌(苏州)股份有限公司 2024-11-29 CN disclosed
CN-114632136-B Skin external composition with enhanced anti-rash effect 浙江养生堂天然药物研究所有限公司 2024-09-27 CN disclosed
CN-118453459-A Fermentation product extract and preparation method and application thereof 浙江立恩生物科技有限公司 2024-08-09 CN disclosed
CN-117357418-A Use of natural products in soothing anti-sensitization cosmetics and anti-sensitization drugs 上海致臻志臣科技有限公司 2024-01-09 CN disclosed
CN-116891515-A Antiallergic peptide and application thereof in immune regulation and antiallergic 绿茵生技股份有限公司 2023-10-17 CN disclosed
CN-113662869-B Compound for promoting extracellular matrix gene expression and preparation method thereof 南京斯拜科生物科技股份有限公司 2023-09-15 CN disclosed
CN-115843293-A Tricyclic compound, preparation method and medical application thereof 中国医药研究开发中心有限公司 2023-03-24 CN disclosed
US-20220370534-A1 EXTERNAL COMPOSITION FOR SKIN HAVING ITCHING RELIEVING EFFECT Yangshengtang (anji) Cosmetics Co., Ltd. (CN) 2022-11-24 US disclosed
CN-114981275-A Tricyclic compound, preparation method and medical application thereof 中国医药研究开发中心有限公司 2022-08-30 CN disclosed
CN-1209319-A Preparation method for medicinal composition containing aza-steroid compound for treating prostatic hyperplasia SANKYO CO (JP) 1999-03-03 CN disclosed
CN-1041095-C Steroid compound and pharmaceutical composition for treating prostatic hypertrophy SANKYO CO (JP) 1998-12-09 CN disclosed
CN-1195666-A Intermediates of steroids, their preparation and uses SANKYO CO (JP) 1998-10-14 CN disclosed
US-4476132-A Acylquinolinone derivatives, and antiallergic preparations and methods of inhibiting allergic reactions using them CIBA-GEIGY CORPORATION (US) 1984-10-09 US disclosed
EP-0034415-B1 1-(CYCLOHEXYL OR CYCLOHEXENYL)-4-ARYL-4-PIPERIDINECARBOXYLIC ACID DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 1984-05-30 EP disclosed
US-4369184-A ANTIHISTAMINES; HETEROCYCLIC NITRILES JANSSEN PHARMACEUTICA N.V. (BE) 1983-01-18 US disclosed
US-4323688-A ANTIALLERGENS CIBA-GEIGY CORPORATION (US) 1982-04-06 US disclosed
US-4322431-A ANTIALLERGENS CIBA-GEIGY CORPORATION (US) 1982-03-30 US disclosed
US-4297358-A AS ANTIALLERGENS CIBA-GEIGY CORPORATION (US) 1981-10-27 US disclosed
EP-0034415-A1 1-(Cyclohexyl or cyclohexenyl)-4-aryl-4-piperidinecarboxylic acid derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1981-08-26 EP disclosed