Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.60 |
| ▸ | HTR1A | P08908 | 5/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 7/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19134583 | 0.89 | MAOB (0.59) | HTR1AKCNH2MAOBAPP | |
| SCHEMBL26154119 | 0.86 | MAOB (0.56) | KCNH2MAOBAPP | |
| SCHEMBL20930997 | 0.85 | MAOB (0.62) | SLC6A2SLC6A4SLC6A3HTR1AKCNH2 | |
| SCHEMBL8484170 | 0.85 | HTR1A (0.54) | SLC6A2SLC6A4SLC6A3HTR1AKCNH2 | |
| Hydrochloric Acid SCHEMBL27038461 | 0.84 | MAOB (0.61) | SLC6A2SLC6A4SLC6A3HTR1AKCNH2 | |
| SCHEMBL8285825 | 0.81 | REN (0.47) | SLC6A2SLC6A4SLC6A3HTR1AKCNH2 | |
| SCHEMBL3045406 | 0.81 | HTR2C (0.51) | SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL3040992 | 0.81 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3HTR1AKCNH2 | |
| SCHEMBL240518 | 0.80 | HTR2C (0.62) | SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL22496024 | 0.80 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3HTR1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061457-A1 | ORGANIC COMPOUNDS | SPEEDEL EXPERIMENTA AG (CH) | 2005-07-07 | — | — | WO | disclosed |