Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.62 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | UBE2M | P61081 | 1/20 | 0.54 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315088 | 0.81 | TSHR (0.72) | MGLLHSD11B1MEN1KMT2ACYP2C19 | |
| SCHEMBL9500153 | 0.79 | MGLL (0.67) | MGLLHSD11B1MEN1KMT2AADRB2 | |
| SCHEMBL9500165 | 0.79 | ACHE (0.67) | MGLLHSD11B1MEN1KMT2ACYP2D6 | |
| SCHEMBL13503785 | 0.78 | MGLL (0.62) | MGLLHSD11B1MEN1KMT2AADRB2 | |
| SCHEMBL8285375 | 0.78 | MGLL (0.59) | MGLLHSD11B1MEN1KMT2AADRB2 | |
| SCHEMBL10726894 | 0.77 | PKM (0.74) | MGLLMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL23775471 | 0.76 | MGLL (0.67) | MGLLHSD11B1MEN1KMT2AADRB2 | |
| SCHEMBL315815 | 0.76 | MGLL (0.67) | MGLLHSD11B1MEN1KMT2AADRB2 | |
| SCHEMBL13202940 | 0.76 | MGLL (0.62) | MGLLHSD11B1MEN1KMT2AADRB2 | |
| SCHEMBL315255 | 0.74 | MEN1 (0.58) | MGLLHSD11B1MEN1KMT2AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005063754-A1 | TRIAZOLE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | PFIZER LIMITED (GB) | 2005-07-14 | — | — | WO | disclosed |