Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRB | O95718 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESRRG | P62508 | 2/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | QDPR | P09417 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2717521 | 0.88 | HRH3 (0.54) | HRH3KCNH2CYP3A4CYP2C9RAB9A | |
| SCHEMBL23250045 | 0.88 | KCNH2 (0.42) | ESRRBESR1ESRRGSLC18A3SIGMAR1 | |
| SCHEMBL11832143 | 0.85 | MAOA (0.55) | SLC18A3SIGMAR1HRH3KCNH2CYP2C9 | |
| SCHEMBL8492021 | 0.84 | SLC18A3 (0.59) | SLC18A3SIGMAR1HRH3KCNH2HTR2C | |
| SCHEMBL22117595 | 0.83 | SLC18A3 (0.48) | SLC18A3SIGMAR1HRH3KCNH2CYP3A4 | |
| SCHEMBL2717763 | 0.83 | HRH3 (0.52) | HRH3KCNH2CYP3A4CYP2C9RAB9A | |
| SCHEMBL8484170 | 0.83 | HTR1A (0.54) | SLC18A3SIGMAR1HRH3KCNH2HTR2C | |
| SCHEMBL8234772 | 0.83 | HTR2C (0.45) | SLC18A3SIGMAR1HRH3KCNH2CYP3A4 | |
| Hydrochloric Acid SCHEMBL22117660 | 0.82 | HTR2C (0.47) | SLC18A3SIGMAR1HRH3KCNH2CYP3A4 | |
| SCHEMBL11519234 | 0.82 | MAOA (0.55) | SLC18A3SIGMAR1HRH3KCNH2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061457-A1 | ORGANIC COMPOUNDS | SPEEDEL EXPERIMENTA AG (CH) | 2005-07-07 | — | — | WO | disclosed |