SCHEMBL857765

SCHEMBL857765

O=C(O)n1cnc2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.61
ASAH1 Q13510 5/20 0.59
KMT2A Q03164 3/20 0.58
LMNA P02545 1/20 0.56
STAT6 P42226 1/20 0.56
HTT P42858 2/20 0.55
MEN1 O00255 1/20 0.54
EGLN3 Q9H6Z9 1/20 0.53
DNMT3A Q9Y6K1 1/20 0.53
NPC1 O15118 1/20 0.51
ALDH1A1 P00352 1/20 0.51
MAPT P10636 1/20 0.51
HPGD P15428 1/20 0.51
RAB9A P51151 1/20 0.51
HSD17B10 Q99714 1/20 0.51
APAF1 O14727 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11443588 0.86 KMT2A (0.60) SMN1; SMN2ASAH1KMT2ALMNASTAT6
SCHEMBL250172 0.86 HTT (0.66) SMN1; SMN2ASAH1KMT2ALMNASTAT6
Valine SCHEMBL8979630 0.83 SMN1; SMN2 (0.53) SMN1; SMN2ASAH1KMT2ALMNASTAT6
Carbamic Acid SCHEMBL10888970 0.83 SMN1; SMN2 (0.56) SMN1; SMN2ASAH1KMT2ALMNASTAT6
SCHEMBL3477048 0.83 KMT2A (0.77) SMN1; SMN2ASAH1KMT2ALMNASTAT6
SCHEMBL3078847 0.82 SMN1; SMN2 (0.59) SMN1; SMN2ASAH1KMT2ALMNASTAT6
SCHEMBL828619 0.82 KMT2A (0.57) SMN1; SMN2ASAH1KMT2ALMNASTAT6
SCHEMBL5133119 0.82 KMT2A (0.57) SMN1; SMN2ASAH1KMT2ALMNASTAT6
SCHEMBL11882632 0.82 KMT2A (0.57) SMN1; SMN2ASAH1KMT2ALMNASTAT6
Bromide SCHEMBL7400039 0.81 KMT2A (0.55) SMN1; SMN2ASAH1KMT2ALMNASTAT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4219460-B1 TRANSGLUTAMINASE 2 (TG2) INHIBITORS SITARI PHARMA INC (US) 2025-02-26 EP claimed
CN-117430738-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN claimed
CN-117430737-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN claimed
US-11804602-B2 Negative electrode for lithium ion secondary battery, and lithium ion secondary battery including same HONDA MOTOR CO., LTD. (JP) 2023-10-31 US claimed
CN-112280143-B Silicon core pipe and preparation method thereof 任丘市长江邮电器材有限公司 2022-09-02 CN claimed
EP-3514147-B1 STEROIDAL COMPOUNDS WITH POTENT ANDROGEN RECEPTOR DOWN-REGULATION AND ANTI PROSTATE CANCER ACTIVITY UNIV MARYLAND (US) 2022-08-03 EP claimed
CN-113372787-A Flame-retardant powder coating and preparation method thereof 廊坊市亚龙三惠科技股份有限公司 2021-09-10 CN claimed
CN-112280143-A Silicon core pipe and preparation method thereof 任丘市长江邮电器材有限公司 2021-01-29 CN claimed
CN-109705115-A A kind of novel thiazole partly flower cyanines class inferior sulfate radical ratio fluorescent probe and its application 泰山医学院 2019-05-03 CN claimed
CN-109694707-A A kind of half flower cyanines class SO of novel indoles32-Ratio fluorescent probe and its application 泰山医学院 2019-04-30 CN claimed
EP-2155676-A2 COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS Commissariat à l'Energie Atomique (FR) 2010-02-24 EP claimed
WO-2008146172-A2 COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2008-12-04 WO claimed
EP-1853604-A2 CHEMICAL COMPOUNDS SmithKline Beecham Corporation (US) 2007-11-14 EP claimed
WO-2006096444-A2 CHEMICAL COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2006-09-14 WO claimed
US-5530121-A IMMUNOSUPPRESSANTS, ANTIINFLAMMATORY AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1996-06-25 US claimed
EP-0332314-B1 SOLVENT EXTRACTION PROCESS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-12-23 EP claimed
US-5128065-A In aqueous environment BETZ LABORATORIES, INC. (US) 1992-07-07 US claimed
EP-0479572-A2 Inhibition of corrosion of copper or copper-bearing metals BETZ EUROPE, INC. (US) 1992-04-08 EP claimed
US-4961856-A CONTACTING AQUEOUS SOLUTION CONTAINING PALLADIUM WITH SOLUTION OF SUBSTITUTED HETEROCYCLIC RING COMPOUND IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-10-09 US claimed
EP-0332314-A2 Solvent extraction process IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-09-13 EP claimed