Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 13/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.51 |
| ▸ | PRKCG | P05129 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | LYN | P07948 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.51 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | MARK3 | P27448 | 1/20 | 0.51 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8287024 | 0.88 | AURKA (0.62) | AURKANPC1MAPTMAPK1RAB9A | |
| SCHEMBL31059888 | 0.88 | AURKA (0.62) | AURKANPC1MAPTMAPK1RAB9A | |
| SCHEMBL8287302 | 0.82 | AURKA (0.51) | AURKANPC1MAPTMAPK1RAB9A | |
| Cardiogenol C SCHEMBL8286309 | 0.77 | ALDH1A1 (0.70) | AURKANPC1MAPTMAPK1RAB9A | |
| Cardiogenol C SCHEMBL29766906 | 0.77 | ALDH1A1 (0.70) | AURKANPC1MAPTMAPK1RAB9A | |
| Cardiogenol C SCHEMBL30628562 | 0.76 | ALDH1A1 (0.68) | AURKANPC1MAPTMAPK1RAB9A | |
| SCHEMBL2604939 | 0.74 | NFE2L2 (0.47) | MAPTMAPK1RAB9ARECQLMCL1 | |
| SCHEMBL29866340 | 0.74 | AURKA (0.66) | AURKANPC1MAPTMAPK1RAB9A | |
| SCHEMBL28398207 | 0.74 | AURKA (0.66) | AURKANPC1MAPTMAPK1RAB9A | |
| SCHEMBL22490561 | 0.72 | STK17A (0.76) | AURKANPC1MAPTMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611457-B2 | Triazine derivatives as differentiation catalysts | TECHNISCHE UNIVERSITAET WIEN (AT) | 2017-04-04 | — | — | US | disclosed |
| US-9611457-B2 | Triazine derivatives as differentiation catalysts | TECHNISCHE UNIVERSITAET WIEN (AT) | 2017-04-04 | — | — | US | disclosed |
| US-20140234965-A1 | TRIAZINE DERIVATIVES AS DIFFERENTIATION CATALYSTS | MEDIZINISCHE UNIVERSITAET WIEN (AT) | 2014-08-21 | — | — | US | disclosed |
| US-20140234965-A1 | TRIAZINE DERIVATIVES AS DIFFERENTIATION CATALYSTS | MEDIZINISCHE UNIVERSITAET WIEN (AT) | 2014-08-21 | — | — | US | disclosed |
| WO-2005068437-A1 | 2, 4 - DIAMINOPYRIMIDINES AND THEIR USE FOR INDUCING CARDIOMYOGENESIS | NOVARTIS AG (CH) | 2005-07-28 | — | — | WO | disclosed |