Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 12/20 | 0.41 |
| ▸ | MAOA | P21397 | 11/20 | 0.41 |
| ▸ | MAOB | P27338 | 11/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10409193 | 0.73 | NFKB1 (0.43) | KDM1AMAOAMAOBGAACYP2C19 | |
| SCHEMBL11700667 | 0.69 | KDM1A (0.51) | KDM1AMAOAMAOBGAASMN1; SMN2 | |
| SCHEMBL5321239 | 0.69 | NFKB1 (0.37) | KDM1AMAOAMAOBCYP2C19KDM4E | |
| SCHEMBL1943935 | 0.69 | KDM1A (0.51) | KDM1AMAOAMAOBGAASMN1; SMN2 | |
| SCHEMBL15767640 | 0.69 | KDM1A (0.51) | KDM1AMAOAMAOBGAASMN1; SMN2 | |
| SCHEMBL485258 | 0.66 | LMNA (0.38) | KDM1AMAOAMAOBSMN1; SMN2KDM4E | |
| SCHEMBL3313168 | 0.66 | OPRK1 (0.36) | MAPK1CYP2C19KDM4EALDH1A1TSHR | |
| SCHEMBL15493407 | 0.66 | KDM1A (0.44) | KDM1AMAOAMAOBTSHR | |
| SCHEMBL2784000 | 0.66 | OPRK1 (0.36) | MAPK1CYP2C19KDM4EALDH1A1TSHR | |
| SCHEMBL2018294 | 0.65 | GAA (0.45) | KDM1AMAOAMAOBGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058808-A1 | N-SUBSTITUTED-N-SULFONYLAMINOCYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2005-06-30 | — | — | WO | disclosed |