SCHEMBL828720

SCHEMBL828720

COc1cccc(CO)c1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.62
ALOX5 P09917 1/20 0.61
PTGS2 P35354 1/20 0.61
MAPT P10636 5/20 0.59
ALDH1A1 P00352 4/20 0.59
KDM4E B2RXH2 3/20 0.59
HPGD P15428 3/20 0.59
CYP3A4 P08684 2/20 0.59
ALOX15 P16050 2/20 0.59
TP53 P04637 2/20 0.59
LMNA P02545 2/20 0.59
ALOX12 P18054 1/20 0.59
MAPK1 P28482 1/20 0.59
HSD17B10 Q99714 1/20 0.59
CALM1 P0DP23 1/20 0.57
GAA P10253 5/20 0.53
GFER P55789 1/20 0.53
TLR2 O60603 1/20 0.48
ERN1 O75460 1/20 0.48
TLR1 Q15399 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14272185 0.93 CALM1 (0.59) IDO1ALOX5PTGS2MAPTALDH1A1
SCHEMBL9576160 0.83 ALOX5 (0.66) IDO1ALOX5PTGS2MAPTALDH1A1
Syringol SCHEMBL20564590 0.82 KDM4E (0.70) IDO1ALOX5PTGS2MAPTALDH1A1
SCHEMBL11725667 0.82 IDO1 (0.61) IDO1ALOX5PTGS2MAPTALDH1A1
SCHEMBL22284783 0.82 IDO1 (0.61) IDO1ALOX5PTGS2MAPTALDH1A1
SCHEMBL29500198 0.82 IDO1 (0.66) IDO1ALOX5PTGS2MAPTALDH1A1
SCHEMBL622754 0.82 IDO1 (0.66) IDO1ALOX5PTGS2MAPTALDH1A1
SCHEMBL622753 0.82 IDO1 (0.66) IDO1ALOX5PTGS2MAPTALDH1A1
SCHEMBL17820 0.80 IDO1 (0.57) IDO1MAPTALDH1A1HPGDTP53
SCHEMBL30829273 0.80 IDO1 (0.57) IDO1MAPTALDH1A1HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113402770-B Method for degrading, recycling and reusing polyurethane 上海鹤城高分子科技有限公司 2023-03-24 CN claimed
CN-113402770-A Method for degrading, recycling and reusing polyurethane 上海鹤城高分子科技有限公司 2021-09-17 CN claimed
EP-2485678-A1 COFERONS AND METHODS OF MAKING AND USING THEM Cornell University (US) 2012-08-15 EP claimed
WO-2011043817-A1 COFERONS AND METHODS OF MAKING AND USING THEM CORNELL UNIVERSITY (US) 2011-04-14 WO claimed
EP-1234046-B1 UDP-GLUCOSE:AGLYCON-GLUCOSYLTRANSFERASE ADELAIDE RES & INNOVATION PTY (AU) 2008-11-12 EP claimed
EP-1341503-B1 AGENT AND METHOD FOR DYEING KERATIN FIBRES WELLA AG (DE) 2008-02-13 EP claimed
US-6835212-B2 Compound with a nucleophilic reaction center, aryl alcohol or benzyl alcohol derivatives and an oxidizing enzyme WELLA AKTIENGESELLSCHAFT (DE) 2004-12-28 US claimed
EP-0934244-B1 METHOD FOR SELECTIVE PREPARATION OF A 2-HYDROXYBENZOIC ACID AND A 4-HYDROXYBENZALDEHYDE AND DERIVATIVES RHODIA CHIMIE SA (FR) 2004-12-15 EP claimed
US-20030041391-A1 Agent and method for dyeing keratin fibres Wella GmbH (DE) 2003-03-06 US claimed
EP-1234046-A2 UDP-GLUCOSE:AGLYCON-GLUCOSYLTRANSFERASE LUMINIS PTY. LIMITED (AU) 2002-08-28 EP claimed
US-6245936-B1 MIXING PHENOLIC COMPOUNDS CARRYING FORMYL OR HYDROXYMETHYL GROUP, ONE IN 2 POSITION AND ONE IN 4 POSITION, SELECTIVELY OXIDIZING GROUP IN 2 POSITION TO CARBOXY GROUP, HYDROXYMETHYL GROUP IN 4 POSITION TO FORMYL GROUP, RECOVERING MIXTURE RHODIA CHIMIE (FR) 2001-06-12 US claimed
WO-2001040491-A2 UDP-GLUCOSE:AGLYCON-GLUCOSYLTRANSFERASE LUMINIS PTY, LIMITED (AU) 2001-06-07 WO claimed
US-6184421-B1 SELECTIVE OXIDATION, TO A CARBOXY GROUP, OF THE GROUP IN THE 2 POSITION WITH RESPECT TO THE HYDROXYL GROUPS OF A MIXTURE OF PHENOLS HAVING FORMYL AND/OR HYDROXYMETHYL GROUPS IN POSITIONS 2 OR 4; PREPARING VANILLIN AND ETHYL VANILLIN RHODIA CHIMIE (FR) 2001-02-06 US claimed
US-6132499-A Inks XEROX CORPORATION (US) 2000-10-17 US claimed
US-6110265-A Ink compositions XEROX CORPORATION (US) 2000-08-29 US claimed
US-6071333-A Ink compositions XEROX CORPORATION (US) 2000-06-06 US claimed
EP-0674232-B1 Recording sheets XEROX CORP (US) 2000-05-31 EP claimed
US-6066200-A COMPRISING A SOLID UREA COMPOUND, AN ALCOHOL, A LIGHTFASTNESS COMPONENT, A LIGHTFAST ANTIOXIDANT, AND A COLORANT XEROX CORPORATION (US) 2000-05-23 US claimed
US-5663022-A Recording sheets XEROX CORPORATION (US) 1997-09-02 US claimed
EP-0674232-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030041391-A1 Agent and method for dyeing keratin fibres KRT18, AKR7A2, ADH5 IDO1 2066/4885ALOX5 1301/4885PTGS2 2678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.