Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 12/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 6/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288295 | 0.88 | MEN1 (0.55) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL13766517 | 0.80 | MAPT (0.45) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL8289216 | 0.72 | PIM1 (0.55) | CRHBPCRHR2ALDH1A1MEN1KMT2A | |
| SCHEMBL3897074 | 0.72 | MAP3K5 (0.68) | CRHBPCRHR2ALDH1A1MAPK1CYP1A2 | |
| SCHEMBL3897077 | 0.72 | MAP3K5 (0.68) | CRHBPCRHR2ALDH1A1MAPK1CYP1A2 | |
| SCHEMBL26458941 | 0.71 | CRHBP (1.00) | CRHBPCRHR2ALDH1A1MAPK1CYP1A2 | |
| SCHEMBL8289161 | 0.71 | MEN1 (0.56) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL23036889 | 0.69 | ALDH1A1 (0.68) | CRHBPCRHR2ALDH1A1MAPK1CYP1A2 | |
| SCHEMBL8289215 | 0.69 | ALDH1A1 (0.49) | CRHBPCRHR2ALDH1A1MAPK1CYP1A2 | |
| SCHEMBL8738469 | 0.69 | ALDH1A1 (1.00) | CRHBPCRHR2ALDH1A1MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005041951-A2 | RHODANINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | RIGEL PHARMACEUTICALS, INC. (US) | 2005-05-12 | — | — | WO | disclosed |