Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 13/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.55 |
| ▸ | POLB | P06746 | 7/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | GALK1 | P51570 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288292 | 0.88 | CRHBP (0.55) | MEN1KMT2APOLBUSP2GALK1 | |
| SCHEMBL13766517 | 0.84 | MAPT (0.45) | MEN1KMT2APOLBUSP2GALK1 | |
| SCHEMBL8289161 | 0.83 | MEN1 (0.56) | MEN1KMT2APOLBUSP2GALK1 | |
| SCHEMBL8289216 | 0.76 | PIM1 (0.55) | MEN1KMT2AMAPTALDH1A1RECQL | |
| SCHEMBL2080494 | 0.74 | MEN1 (0.82) | MEN1KMT2APOLBUSP2GALK1 | |
| SCHEMBL2080496 | 0.74 | MEN1 (0.82) | MEN1KMT2APOLBUSP2GALK1 | |
| SCHEMBL13082002 | 0.72 | KMT2A (0.51) | MEN1KMT2APOLBMAPT | |
| SCHEMBL8290402 | 0.71 | MEN1 (0.42) | MEN1KMT2AUSP2MAPTMAPK1 | |
| SCHEMBL13081954 | 0.70 | PLG (0.49) | MEN1KMT2APOLBUSP2MAPT | |
| SCHEMBL12010971 | 0.69 | MEN1 (1.00) | MEN1KMT2APOLBUSP2GALK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005041951-A2 | RHODANINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | RIGEL PHARMACEUTICALS, INC. (US) | 2005-05-12 | — | — | WO | disclosed |