Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AIP | O00170 | 1/20 | 0.76 |
| ▸ | SGTA | O43765 | 1/20 | 0.76 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.76 |
| ▸ | STIP1 | P31948 | 1/20 | 0.76 |
| ▸ | PPP5C | P53041 | 1/20 | 0.76 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.76 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.76 |
| ▸ | FKBP8 | Q14318 | 1/20 | 0.76 |
| ▸ | TOMM34 | Q15785 | 1/20 | 0.76 |
| ▸ | DNAJC7 | Q99615 | 1/20 | 0.76 |
| ▸ | STUB1 | Q9UNE7 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 13/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.65 |
| ▸ | MAPT | P10636 | 12/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.65 |
| ▸ | POLB | P06746 | 10/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 9/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.65 |
| ▸ | HPGD | P15428 | 7/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13856578 | 0.79 | MEN1 (1.00) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL13856429 | 0.78 | MEN1 (1.00) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL8288571 | 0.78 | MAPK1 (0.69) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL13856422 | 0.78 | MEN1 (1.00) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL26293025 | 0.75 | KMT2A (0.73) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL26293192 | 0.74 | MEN1 (0.85) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL15814086 | 0.74 | MEN1 (0.84) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL26295615 | 0.74 | KMT2A (0.75) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL1895132 | 0.74 | MEN1 (0.77) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL26294531 | 0.73 | MEN1 (0.76) | AIPSGTATOMM70STIP1PPP5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |