Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.98 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | FLT3 | P36888 | 7/20 | 0.70 |
| ▸ | TP53 | P04637 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289500 | 0.99 | RXFP1 (1.00) | RXFP1MEN1KMT2AFLT3TP53 | |
| SCHEMBL5460296 | 0.88 | FLT3 (0.80) | RXFP1MEN1KMT2AFLT3TP53 | |
| SCHEMBL8289432 | 0.86 | KMT2A (1.00) | RXFP1MEN1KMT2AFLT3LMNA | |
| SCHEMBL8289434 | 0.85 | RXFP1 (0.75) | RXFP1MEN1KMT2ATP53MAPT | |
| SCHEMBL8290774 | 0.85 | KMT2A (0.98) | RXFP1MEN1KMT2AFLT3MAPT | |
| SCHEMBL8289502 | 0.83 | KMT2A (0.75) | RXFP1MEN1KMT2AFLT3TP53 | |
| SCHEMBL5453222 | 0.83 | FLT3 (1.00) | RXFP1MEN1KMT2AFLT3TP53 | |
| SCHEMBL8290377 | 0.82 | FLT3 (1.00) | RXFP1MEN1KMT2AFLT3TP53 | |
| SCHEMBL5446246 | 0.81 | FLT3 (0.73) | RXFP1MEN1KMT2AFLT3MAPT | |
| SCHEMBL8289809 | 0.80 | FLT3 (0.96) | RXFP1MEN1KMT2AFLT3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |