Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.98 |
| ▸ | MEN1 | O00255 | 3/20 | 0.98 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.75 |
| ▸ | FLT3 | P36888 | 10/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289432 | 0.99 | KMT2A (1.00) | KMT2AMEN1RXFP1FLT3RECQL | |
| SCHEMBL15272661 | 0.86 | MEN1 (0.77) | KMT2AMEN1RXFP1FLT3RECQL | |
| SCHEMBL5460296 | 0.86 | FLT3 (0.80) | KMT2AMEN1RXFP1FLT3L3MBTL1 | |
| SCHEMBL8289500 | 0.86 | RXFP1 (1.00) | KMT2AMEN1RXFP1FLT3L3MBTL1 | |
| SCHEMBL8290414 | 0.85 | MEN1 (0.75) | KMT2AMEN1RXFP1FLT3RECQL | |
| SCHEMBL8288681 | 0.85 | RXFP1 (0.98) | KMT2AMEN1RXFP1FLT3L3MBTL1 | |
| SCHEMBL8289502 | 0.84 | KMT2A (0.75) | KMT2AMEN1RXFP1FLT3RECQL | |
| SCHEMBL24425732 | 0.82 | FLT3 (1.00) | KMT2AMEN1FLT3RECQLMAPT | |
| SCHEMBL8290405 | 0.82 | FLT3 (1.00) | KMT2AMEN1FLT3RECQLALDH1A1 | |
| SCHEMBL30148150 | 0.82 | FLT3 (1.00) | KMT2AMEN1FLT3RECQLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |