Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.75 |
| ▸ | MEN1 | O00255 | 4/20 | 0.75 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.70 |
| ▸ | FLT3 | P36888 | 10/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289481 | 0.85 | MAPT (0.61) | KMT2AMEN1RXFP1MAPTTP53 | |
| SCHEMBL8289432 | 0.85 | KMT2A (1.00) | KMT2AMEN1RXFP1FLT3RECQL | |
| SCHEMBL5460296 | 0.85 | FLT3 (0.80) | KMT2AMEN1RXFP1FLT3MAPT | |
| SCHEMBL8290774 | 0.84 | KMT2A (0.98) | KMT2AMEN1RXFP1FLT3MAPT | |
| SCHEMBL8288681 | 0.83 | RXFP1 (0.98) | KMT2AMEN1RXFP1FLT3MAPT | |
| SCHEMBL8289500 | 0.82 | RXFP1 (1.00) | KMT2AMEN1RXFP1FLT3MAPT | |
| SCHEMBL22095967 | 0.78 | FLT3 (1.00) | KMT2AMEN1FLT3MAPTTP53 | |
| SCHEMBL5458963 | 0.77 | FLT3 (0.71) | KMT2AMEN1RXFP1FLT3MAPT | |
| SCHEMBL8290405 | 0.77 | FLT3 (1.00) | KMT2AMEN1FLT3MAPTTP53 | |
| SCHEMBL29766887 | 0.77 | FLT3 (1.00) | KMT2AMEN1FLT3MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |