Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | AR | P10275 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.48 |
| ▸ | PTPRF | P10586 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5919019 | 0.83 | PRKCZ (0.61) | PRKCZMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11518208 | 0.81 | PRKCZ (1.00) | PRKCZMAPTARALDH1A1TSHR | |
| SCHEMBL8290370 | 0.78 | MAPT (0.68) | PRKCZMAPTALDH1A1LMNACYP1A2 | |
| SCHEMBL13837643 | 0.75 | ANO1 (0.58) | PRKCZMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL20690582 | 0.74 | ALDH1A1 (0.67) | MAPTALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL1554606 | 0.73 | PRKCZ (0.73) | PRKCZMAPTALDH1A1LMNATSHR | |
| SCHEMBL9754581 | 0.71 | PRKCZ (0.60) | PRKCZMAPTARALDH1A1MAPK1 | |
| SCHEMBL23599197 | 0.70 | LMNA (0.74) | MAPTALDH1A1LMNACYP3A4CYP2C9 | |
| SCHEMBL276323 | 0.70 | AR (0.56) | PRKCZMAPTARSMN1; SMN2RAB9A | |
| SCHEMBL14123489 | 0.70 | PRKCZ (0.63) | PRKCZMAPTALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |