Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | KIF11 | P52732 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | RORC | P51449 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8290715 | 0.87 | ALDH1A1 (0.69) | ALDH1A1HSD17B10ALOX15KDM4EMEN1 | |
| SCHEMBL5859249 | 0.85 | KIF11 (0.55) | ALDH1A1HSD17B10ALOX15KDM4EKIF11 | |
| SCHEMBL23413421 | 0.82 | ALDH1A1 (0.77) | ALDH1A1HSD17B10ALOX15KDM4EMEN1 | |
| SCHEMBL5452093 | 0.81 | ALDH1A1 (0.95) | ALDH1A1HSD17B10ALOX15KDM4EMEN1 | |
| SCHEMBL5857713 | 0.80 | KIF11 (0.55) | ALDH1A1HSD17B10ALOX15KDM4EKIF11 | |
| SCHEMBL8289801 | 0.79 | ALDH1A1 (1.00) | ALDH1A1HSD17B10ALOX15KDM4EMEN1 | |
| SCHEMBL5856637 | 0.78 | KIF11 (0.50) | ALDH1A1HSD17B10ALOX15KDM4EKIF11 | |
| SCHEMBL3982516 | 0.77 | ALDH1A1 (0.69) | ALDH1A1HSD17B10ALOX15KDM4EMEN1 | |
| SCHEMBL3980443 | 0.77 | ALDH1A1 (1.00) | ALDH1A1HSD17B10ALOX15KDM4EMEN1 | |
| SCHEMBL6834944 | 0.75 | ALDH1A1 (0.96) | ALDH1A1HSD17B10ALOX15KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |