Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 8/20 | 0.42 |
| ▸ | CNR2 | P34972 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859249 | 0.89 | KIF11 (0.55) | KIF11MEN1KMT2ACNR1CNR2 | |
| SCHEMBL5858179 | 0.86 | CNR2 (0.43) | CNR1CNR2ALDH1A1TSHRMAPT | |
| SCHEMBL5859337 | 0.86 | ANO1 (0.45) | KIF11CNR1CNR2ALDH1A1LMNA | |
| SCHEMBL5857629 | 0.86 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL5856399 | 0.86 | KIF11 (0.49) | KIF11MEN1KMT2ACNR2ALDH1A1 | |
| SCHEMBL5856651 | 0.85 | CNR2 (0.55) | MEN1KMT2ACNR1CNR2ALDH1A1 | |
| SCHEMBL5856924 | 0.85 | CNR2 (0.44) | CNR1CNR2ALDH1A1ANO1KDM4E | |
| SCHEMBL5857663 | 0.83 | CNR2 (0.44) | CNR1CNR2LMNA | |
| SCHEMBL8290376 | 0.78 | ALDH1A1 (0.65) | KIF11MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5856947 | 0.77 | MAPT (0.41) | KIF11CNR1CNR2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071215-B2 | Anthelmintic and insecticidal compositions | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-07-04 | — | — | US | claimed |
| EP-1569941-A1 | ANTHELMINTIC AND INSECTICIDAL THIOHENE COMPOSITIONS | Pharmacia & Upjohn Company LLC (US) | 2005-09-07 | — | — | EP | claimed |
| US-20040127548-A1 | Novel anthelmintic and insecticidal compositions | LEE BYUNG HYUN (US) | 2004-07-01 | — | — | US | claimed |
| WO-2004035591-A1 | ANTHELMINTIC AND INSECTICIDAL THIOHENE COMPOSITIONS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-04-29 | — | — | WO | claimed |
| US-7071215-B2 | Anthelmintic and insecticidal compositions | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-07-04 | — | — | US | disclosed |
| US-20040127548-A1 | Novel anthelmintic and insecticidal compositions | LEE BYUNG HYUN (US) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127548-A1 | Novel anthelmintic and insecticidal compositions | ACHE, BCHE, AADAC | KIF11 2454/4885MEN1 4773/4885KMT2A 3240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.