Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.53 |
| ▸ | MAPT | P10636 | 11/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | HPGD | P15428 | 8/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 5/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3911820 | 0.80 | GAA (0.61) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL3913969 | 0.76 | FLT3 (0.64) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL8289722 | 0.76 | PDE4B (0.52) | ALDH1A1MAPTKDM4EHSD17B10MEN1 | |
| SCHEMBL22543334 | 0.76 | LIMK1 (0.39) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL8288690 | 0.74 | PDE4B (0.58) | KDM4EMEN1KMT2AMAPK1PDE4B | |
| SCHEMBL8288836 | 0.74 | PDE4B (0.57) | KDM4EMEN1KMT2AMAPK1PDE4B | |
| SCHEMBL22543319 | 0.73 | ABCC1 (0.38) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL14829495 | 0.72 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL21603773 | 0.71 | ALDH1A1 (0.61) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL5449503 | 0.70 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |