Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 16/20 | 0.47 |
| ▸ | MAPT | P10636 | 14/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.47 |
| ▸ | HPGD | P15428 | 10/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2162573 | 0.83 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL2162345 | 0.81 | CNR1 (0.38) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL2162393 | 0.81 | CNR1 (0.38) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL2162192 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDHSD17B10MEN1 | |
| SCHEMBL2162281 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL2162435 | 0.76 | ALDH1A1 (0.37) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL5453373 | 0.75 | FLT3 (0.54) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL20339216 | 0.74 | ALOX15 (0.42) | MAPTALOX15MEN1KMT2ALMNA | |
| SCHEMBL8290782 | 0.70 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL22624336 | 0.64 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | disclosed |
| EP-1670804-A2 | HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | GPC Biotech AG (DE) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005023818-A2 | HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | GPC BIOTECH AG (DE) | 2005-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | TBCA, PARK7, NFATC1 | ALDH1A1 1153/4885MAPT 21/4885KDM4E 3417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.