Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8290780 | 0.89 | TP53 (0.60) | THRBMAPTRXFP1ANO1TSHR | |
| SCHEMBL13438093 | 0.76 | MAPT (0.64) | THRBMAPTMEN1KMT2AANO1 | |
| SCHEMBL10857636 | 0.74 | NOTUM (0.70) | NPSR1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL9722109 | 0.73 | ALDH1A1 (0.72) | NPSR1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL10344531 | 0.72 | MEN1 (0.65) | NPSR1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL4908222 | 0.71 | MAPT (0.71) | NPSR1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL11475652 | 0.71 | SMN1; SMN2 (0.69) | THRBNPSR1MAPTL3MBTL1MEN1 | |
| SCHEMBL11872902 | 0.71 | MEN1 (0.68) | NPSR1MAPTMEN1KMT2ATSHR | |
| SCHEMBL13659474 | 0.70 | TSHR (0.69) | THRBNPSR1MAPTL3MBTL1MEN1 | |
| Metaxon SCHEMBL117877 | 0.70 | TDP1 (0.70) | NPSR1MAPTMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |