Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289729 | 0.92 | MAPT (0.67) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL8288727 | 0.89 | MAPT (0.64) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL8290780 | 0.88 | TP53 (0.60) | MAPTTP53ANO1ALDH1A1HPGD | |
| SCHEMBL34468610 | 0.86 | TP53 (0.67) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL34468504 | 0.84 | ALDH1A1 (0.66) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL34468585 | 0.82 | TNKS2 (0.67) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL8288732 | 0.79 | POLB (0.78) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL3489776 | 0.78 | ALDH1A1 (0.64) | MAPTTP53KDM4EANO1ALDH1A1 | |
| SCHEMBL8290887 | 0.76 | THRB (0.55) | MAPTTP53ANO1HPGDTSHR | |
| SCHEMBL24349086 | 0.75 | ANO1 (1.00) | MAPTANO1ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8486863-B2 | Activators of lateral root formation | VIB VZW (BE) | 2013-07-16 | — | — | US | disclosed |
| US-20100105561-A1 | ACTIVATORS OF LATERAL ROOT FORMATION | UNIVERSITEIT GENT (BE) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105561-A1 | ACTIVATORS OF LATERAL ROOT FORMATION | CROCC, ARFIP2, RALA | MAPT 4049/4885TP53 4441/4885KDM4E 2790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.