Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.40 |
| ▸ | PSMB9 | P28065 | 5/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | TERF2 | Q15554 | 6/20 | 0.34 |
| ▸ | BACE1 | P56817 | 4/20 | 0.33 |
| ▸ | PPIA | P62937 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8290694 | 0.87 | CTSD (0.38) | CTSDBACE1GAA | |
| SCHEMBL8289459 | 0.86 | ADAM17 (0.35) | CTSDBACE1 | |
| SCHEMBL12856032 | 0.83 | PPIA (0.38) | CTSDPSMB9PSMB8TERF2PPIA | |
| SCHEMBL12856064 | 0.80 | CTSD (0.43) | CTSDPSMB9PSMB8BACE1GAA | |
| SCHEMBL13685135 | 0.78 | BACE1 (0.35) | CTSDBACE1 | |
| SCHEMBL8290344 | 0.77 | CTSD (0.41) | CTSDBACE1GAA | |
| SCHEMBL12856031 | 0.77 | GAA (0.42) | CTSDPSMB9PSMB8TERF2PPIA | |
| SCHEMBL8035850 | 0.76 | ADAM17 (0.37) | CTSDBACE1 | |
| SCHEMBL8290665 | 0.76 | GAA (0.42) | CTSDPSMB9PSMB8TERF2PPIA | |
| SCHEMBL12856057 | 0.75 | CTSD (0.37) | CTSDBACE1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030796-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORPORATION (US) | 2005-04-07 | — | — | WO | disclosed |