Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 16/20 | 0.43 |
| ▸ | TACR2 | P21452 | 2/20 | 0.43 |
| ▸ | TACR3 | P29371 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8296290 | 0.81 | TACR1 (0.50) | TACR1TACR2TACR3 | |
| SCHEMBL8593224 | 0.78 | TACR2 (0.44) | TACR1TACR2 | |
| SCHEMBL8292835 | 0.78 | TACR1 (0.56) | TACR1TACR2TACR3 | |
| SCHEMBL8300817 | 0.74 | TACR1 (0.57) | TACR1TACR2TACR3 | |
| SCHEMBL8591901 | 0.71 | OPRD1 (0.46) | TACR1TACR2 | |
| SCHEMBL7846543 | 0.70 | TACR1 (0.47) | TACR1TACR2TACR3 | |
| SCHEMBL7817576 | 0.69 | TACR1 (0.82) | TACR1TACR2 | |
| SCHEMBL8296291 | 0.68 | TACR1 (0.63) | TACR1TACR2TACR3 | |
| SCHEMBL8300343 | 0.68 | TACR1 (0.75) | TACR1TACR2TACR3 | |
| SCHEMBL8563879 | 0.67 | TACR1 (0.49) | TACR1TACR2TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512901-B1 | Aminated polycyclic compounds and their enantiomers, process for their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1999-06-23 | — | — | EP | disclosed |
| US-5770735-A | Polycyclic amine compounds and their enantiomers, their method of preparation and pharmaceutical compositions in which they are present | ELF SANOFI (FR) | 1998-06-23 | — | — | US | disclosed |
| US-5340822-A | Substance P, neurokinin antagonists | ELF SANOFI (FR) | 1994-08-23 | — | — | US | disclosed |
| EP-0512901-A1 | Aminated polycyclic compounds and their enantiomers, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1992-11-11 | — | — | EP | disclosed |