Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.51 |
| ▸ | HTR3B | O95264 | 3/20 | 0.51 |
| ▸ | HTR3A | P46098 | 3/20 | 0.51 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.51 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441918 | 0.75 | HTR3E (0.53) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7118324 | 0.72 | NPC1 (0.51) | — | |
| SCHEMBL7361204 | 0.72 | HTR3A (0.55) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7276197 | 0.71 | HTR3E (0.49) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7279707 | 0.71 | HTR3E (0.49) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9646418 | 0.71 | HTR3A (0.66) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL5055931 | 0.71 | CHRNA7 (0.70) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7279745 | 0.69 | HTR3A (0.47) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL1649473 | 0.68 | HTR3A (0.67) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Renzapride SCHEMBL678616 | 0.68 | HTR3A (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005023808-A2 | PROCESS FOR THE PREPARATION OF RENZAPRIDE AND INTERMEDIATES THEREOF | ALIZYME THERAPEUTICS LIMITED (GB) | 2005-03-17 | — | — | WO | disclosed |