Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 18/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 17/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 15/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8293186 | 0.82 | HSD17B10 (0.44) | HDAC2HDAC1HDAC3 | |
| SCHEMBL8293148 | 0.80 | ERN1 (0.46) | HDAC2HDAC1HDAC3 | |
| SCHEMBL8292829 | 0.79 | LRRK2 (0.33) | — | |
| SCHEMBL386245 | 0.75 | HDAC2 (0.49) | KCNH2HDAC2HDAC1HDAC3 | |
| SCHEMBL8348073 | 0.73 | FDPS (0.46) | — | |
| SCHEMBL29598145 | 0.70 | KCNH2 (1.00) | KCNH2HDAC2HDAC1HDAC3LTA4H | |
| SCHEMBL2873589 | 0.70 | KCNH2 (1.00) | KCNH2HDAC2HDAC1HDAC3LTA4H | |
| SCHEMBL3467228 | 0.70 | KCNH2 (0.70) | KCNH2HDAC2HDAC1HDAC3LTA4H | |
| SCHEMBL1065997 | 0.70 | KCNH2 (0.70) | KCNH2HDAC2HDAC1HDAC3LTA4H | |
| SCHEMBL1066547 | 0.69 | KCNH2 (0.55) | KCNH2HDAC2HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030704-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2005-04-07 | — | — | WO | disclosed |