Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8292829 | 0.88 | LRRK2 (0.33) | HSD17B10MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL8348073 | 0.79 | FDPS (0.46) | KDM4EALDH1A1HPGDALOX15CYP3A4 | |
| SCHEMBL15146119 | 0.76 | TAAR1 (0.41) | ALDH1A1HPGDLMNAGAAHTT | |
| SCHEMBL4888958 | 0.73 | MAPT (0.53) | HSD17B10MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL31570069 | 0.73 | MAPT (0.53) | HSD17B10MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL27529111 | 0.73 | IKBKB (0.43) | HSD17B10MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL28810478 | 0.72 | KDM4E (0.40) | HSD17B10MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL3793580 | 0.72 | HSD17B10 (0.57) | HSD17B10MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL3785609 | 0.70 | HSD17B10 (0.53) | HSD17B10MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL15508767 | 0.69 | PRKCI (0.38) | MAPTKDM4EALDH1A1ALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030704-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2005-04-07 | — | — | WO | disclosed |